Tag: leakygut

Another Promising Treatment for Leaky Gut?

Researchers at Wake Forest School of Medicine (in North Carolina), have discovered that using inactivated (dead via the application of heat) Lactobacillus paracasei (derived from humans) appears to have a remarkably beneficial effect in an animal model of leaky gut, thereby reducing inflammation.[i]  In…

The Microbiome and the Basal Ganglia in …The Case of the Leaky Gut?

I recently read an article looking at the effects of bacterial microbiome alterations on particular circuits in the brain (the thalamo-cortico-basal ganglia)  that are associated with compulsive behavior, addiction, altered sensations and motor output.[i]  What struck me is how closely related seemingly unrelated disorders…

Histamine Intolerance and the Altered Micobiome

A week or so ago, a reader wrote to me asking if I had ever heard of an intolerance to fermented foods.  Indeed I had:  histamine intolerance.  I have worked with a very few nutrition clients over the years who have suffered from this…

The Two Sides of Bacteroides fragilis

Back in May, 2018, I wrote about Bacteriodes fragilis (B. fragilis), a species of bacteria some strains of which are toxic, some of which are highly beneficial.  The main thrust of that post was about how our immune system, when functioning properly, can recognize…

Irritable Bowel: SIBO, Dysbiosis and Diet

In 2010, I read a paper in the journal, Nutrition, that really rocked my world:  “The concept of small intestinal bacterial overgrowth (SIBO) in relation to functional gastrointestinal disorders.” [i]  To summarize one of its many key points:  we don’t know how to test…

Constipation, Dysbiosis, Autism and a Prebiotic: A New Clinical Trial

The single most common gastrointestinal (GI) complaint I hear as a nutritionist, by a long way, is constipation…and the single best piece of advice I give my clients is “drink more water.”  It never ceases to amaze me how dehydrated most people are.  Invariably,…

Food Processing: Another Suspect in the ‘Globesity’ Epidemic?

Last night, I read an article that fit absolutely perfectly into my unintentional but prominent theme of the last couple of weeks:  the relationship of the microbiome to weight issues…and to food:  “Food Processing, Gut Microbiota and the Globesity Problem.”[i]  Yup – we face…

Some Early-Stage, But Promising, Science About the Microbiome and Cancer

Yesterday morning, I posted a story on my Biome Buzz’ Facebook page about 2 new studies that independently showed that there is a distinctive microbiome composition associated with colorectal cancer.[i]  One study “…identified a set of 29 species indicative of colorectal cancer across 7…

More on Autism and the Microbiome…and a Clinical Study Using Probiotics

My Monday afternoon was devoted to reading two articles about the microbiome and autism.  The first was a chapter from a book on biological markers found in psychiatric and neurodegenerative disease.[i]  I’ve chosen what I thought were the top 10 points from this article…

A Probiotic/Colostrum Pilot Study in Autism…Which Likely Has Clinical Implications in Other Inflammatory Illnesses

Yesterday, I read a cool little pilot study[i] out of the University of California, testing the tolerability and efficacy of a probiotic and bovine colostrum on a small group of children with autism.  And while the results on this population were interesting, as I’ll…