Tag: brain

More On Propionic Acid and Autism (or…I’m sorry, but I Can’t Help Myself…)

I know that everyone (including me) wants answers to the question “how do you fix a broken biome.”  I am always happy when I come across any information that may actually help people, especially since, at this point, there’s precious little known about how…

New Research into the Negative Side of Short-Chain Fatty Acids: Too Much of a Good Thing

I have spent a fair bit of virtual ink over the years talking about both the positives and the negatives of short chain fatty acids (SCFAs), mentioning that indeed, you really can have too much of a good thing.  For example, as healthy as…

FMT and Autism: A Status Report

Over the weekend I read an interesting little article on the status of fecal microbiota transplant as a therapy for treating autism.[i]  It most certainly is one of the more promising treatments:  the two clinical trials so far have had pretty spectacular results.  That’s…

Organophosphates: Yet Another Environmental Toxin that Adversely Affects the Gut Biome and Health

Another popular request, courtesy of the survey I ran a couple of weeks ago, was for more information on how environmental toxins may affect the human biome.  I wrote about the herbicide, glyphosate (that’s found in Roundup), several months ago, and while the role…

The Microbiome and the Basal Ganglia in …The Case of the Leaky Gut?

I recently read an article looking at the effects of bacterial microbiome alterations on particular circuits in the brain (the thalamo-cortico-basal ganglia)  that are associated with compulsive behavior, addiction, altered sensations and motor output.[i]  What struck me is how closely related seemingly unrelated disorders…

Glyphosate and Human Health: Is the Bacterial Microbiome the Connection?

In various posts, I’ve explored different potential mechanisms that may play a part in the epidemic of biome alterations we have experienced in the industrialized world, including diet, formula feeding, chronic stress, and so forth.  Another potential mechanism, environmental toxins, is another area of…

Ameliorating the Adverse Effects of Excess Propionic Acid

I am officially declaring this Biome Buzz’ first annual Propionic Acid Week! (Unfortunately, this is not a cause for celebration.) If you remember, propionic acid (PPA) is a short-chain fatty acid produced by gut bacteria.  Ordinarily, PPA , like the other SCFAs, is great…

Is There Any Doubt Left that Propionic Acid is a Cause of Autism? Apparently not

I first started to write about autism and propionic acid (PPA) not long after creating this blog, back in the fall of 2016.  In January 2017, I described to you some of the work of Dr. Derrick MacFabe, which as particularly fascinated me for…

The Two Sides of Bacteroides fragilis

Back in May, 2018, I wrote about Bacteriodes fragilis (B. fragilis), a species of bacteria some strains of which are toxic, some of which are highly beneficial.  The main thrust of that post was about how our immune system, when functioning properly, can recognize…

Neurodegnerative and Neuropsychiatric Disorders: Prime Targets for Helminths

Within just a few weeks of each other, two papers have been published looking at the potential of using helminths to treat neurological conditions.  Not surprisingly, both focus on the powerful anti-inflammatory effect of helminths. (For those of you new to helminths:  these are…