Tag: autism

The Microbiome and the Basal Ganglia in …The Case of the Leaky Gut?

I recently read an article looking at the effects of bacterial microbiome alterations on particular circuits in the brain (the thalamo-cortico-basal ganglia)  that are associated with compulsive behavior, addiction, altered sensations and motor output.[i]  What struck me is how closely related seemingly unrelated disorders…

Glyphosate and Human Health: Is the Bacterial Microbiome the Connection?

In various posts, I’ve explored different potential mechanisms that may play a part in the epidemic of biome alterations we have experienced in the industrialized world, including diet, formula feeding, chronic stress, and so forth.  Another potential mechanism, environmental toxins, is another area of…

The Promise of Fecal Microbiota Transplant

Over the weekend, I read a great little article about the potential applications of fecal microbiota transplant (FMT) in treating a huge variety of diseases.[i]  Of course, we are sorely lacking in clinical trials for almost all but still, there is hope to be…

Prebiotics: Yet Another Layer of Biome Complexity

I regularly receive FB messages and emails from people asking me what probiotic or prebiotic they should be taking.  If I knew the answer, I’d be rich.  The answer is…no one knows.  We are so at the tip of the iceberg on all this,…

Propionic Acid: A Culprit in Obesity and Metabolic Dysfunction?

As promised on Tuesday, today is the last post in my continuing propionic acid series  as we wrap up not-celebrating the Biome Buzz’ official First Annual Propionic Acid week.  Today’s post is about just how suspect it is for all our health. A study…

Ameliorating the Adverse Effects of Excess Propionic Acid

I am officially declaring this Biome Buzz’ first annual Propionic Acid Week! (Unfortunately, this is not a cause for celebration.) If you remember, propionic acid (PPA) is a short-chain fatty acid produced by gut bacteria.  Ordinarily, PPA , like the other SCFAs, is great…

Is There Any Doubt Left that Propionic Acid is a Cause of Autism? Apparently not

I first started to write about autism and propionic acid (PPA) not long after creating this blog, back in the fall of 2016.  In January 2017, I described to you some of the work of Dr. Derrick MacFabe, which as particularly fascinated me for…

The Two Sides of Bacteroides fragilis

Back in May, 2018, I wrote about Bacteriodes fragilis (B. fragilis), a species of bacteria some strains of which are toxic, some of which are highly beneficial.  The main thrust of that post was about how our immune system, when functioning properly, can recognize…

Neurodegnerative and Neuropsychiatric Disorders: Prime Targets for Helminths

Within just a few weeks of each other, two papers have been published looking at the potential of using helminths to treat neurological conditions.  Not surprisingly, both focus on the powerful anti-inflammatory effect of helminths. (For those of you new to helminths:  these are…

Autism and Clostridia: Mounting Evidence of a Connection

As you know, I’ve been following the research of Dr. Derrick MacFabe for well over a decade now.  I’ve described it before on this blog, several times, including this first post 2 ½ years ago – to which, if you remember, Dr. MacFabe was…