Tag: allergy

The Deworming Question: A Good Idea? Pointless? Detrimental? The Evidence Mounts…

Last month, a meta-analysis paper came out searching the medical literature through the year 2018, looking for evidence of the benefits promised by the worldwide efforts at deworming school children, recommended by all global advocacy organizations including WHO.  The authors, from the Department of…

The Promise of Fecal Microbiota Transplant

Over the weekend, I read a great little article about the potential applications of fecal microbiota transplant (FMT) in treating a huge variety of diseases.[i]  Of course, we are sorely lacking in clinical trials for almost all but still, there is hope to be…

Allergy and Asthma Risk in Children: A Gut Bacteria Metabolite Culprit Identified

Two weeks ago, I wrote  about a retrospective study out of Loyola University in which researchers looked at the relationship of the early introduction of antibiotics to the development of allergy and asthma. If you recall, they found, “Exposure to these medicines in their…

Antibiotics in Early Childhood: The Road to Asthma and Allergy

When my son was just 36 hours old, he was re-hospitalized with a fever and put onto 5 days of IV antibiotics.  (You can read more about his history here.)  He was given more oral antibiotics right before his first birthday. Once I learned…

Helminth Therapy: A Call to Action

An interesting opinion piece by Dr. William Parker, of Duke University, and colleagues at a couple of Czech Universities, just appeared in Trends in Parasitology.[i]  To summarize, the paper makes two key points: A.  These scientists hold the belief that the interaction between human…

Evolutionary Mismatch, the Human Biome…and a Bit More on Obesity

Recently there was a lot of discussion on the Biome Buzz’ Facebook page in regards to a post on obesity, wherein some people expressed their opinions that our current epidemic of obesity is due to nothing more than people eating too much junk food. …

Early Life Biome Depletion and a Lifetime of Health Issues

Yesterday, I found a great complimentary article[i] to my Tuesday post regarding lack of exposure to commensal organisms and the development of asthma in children.  This is another “it’s biome depletion not the darn ‘hygiene hypothesis’” kind of story! Background information:   babies are exposed…

The “Hygiene Hypothesis” – A Phrase Whose Time Has Passed

Dr. William Parker of Duke University Medical School, an eminent researcher into the effects of helminths on the immune system among other specialties, wrote a commentary in 2014 in the British Medical Journal entitled, The “hygiene hypothesis” for allergic disease is a misnomer.[i]  His…

Food Allergy, the Microbiome and Epigenetics

Last week I wrote about how nitric oxide, a communication molecule naturally produced by our bodies, is also produced by the bacteria of our gut.  The molecule attaches to thousands of proteins in our bodies and can turn genes on and off, greatly affecting…

A Trio of New Helminth Papers

Three articles were recently published on helminths that are worth sharing with you.  Two studied the immune effects (in rodents) of the species, Hymenolepis diminuta.  (This species is native to rodents and one currently used in helminthic therapy.) The third summarized research into using…