Category: Mental Health

New Research into the Negative Side of Short-Chain Fatty Acids: Too Much of a Good Thing

I have spent a fair bit of virtual ink over the years talking about both the positives and the negatives of short chain fatty acids (SCFAs), mentioning that indeed, you really can have too much of a good thing.  For example, as healthy as…

FMT and Autism: A Status Report

Over the weekend I read an interesting little article on the status of fecal microbiota transplant as a therapy for treating autism.[i]  It most certainly is one of the more promising treatments:  the two clinical trials so far have had pretty spectacular results.  That’s…

Organophosphates: Yet Another Environmental Toxin that Adversely Affects the Gut Biome and Health

Another popular request, courtesy of the survey I ran a couple of weeks ago, was for more information on how environmental toxins may affect the human biome.  I wrote about the herbicide, glyphosate (that’s found in Roundup), several months ago, and while the role…

The Microbiome and the Basal Ganglia in …The Case of the Leaky Gut?

I recently read an article looking at the effects of bacterial microbiome alterations on particular circuits in the brain (the thalamo-cortico-basal ganglia)  that are associated with compulsive behavior, addiction, altered sensations and motor output.[i]  What struck me is how closely related seemingly unrelated disorders…

Fecal Microbiota Transplant: the Answer for Alzheimer’s Disease?

Ok, yeah…more on fecal microbiota transplants (FMT).  This is my obsession for the week. But after reading my last post…can you blame me?! In that post, in case you missed it, I talked about a new article reviewing the potential of FMT to treat…

The Promise of Fecal Microbiota Transplant

Over the weekend, I read a great little article about the potential applications of fecal microbiota transplant (FMT) in treating a huge variety of diseases.[i]  Of course, we are sorely lacking in clinical trials for almost all but still, there is hope to be…

Probiotics for Chronic Fatigue and Fibromyalgia? Probably, but the Science Isn’t Yet There

As regular readers know, I’m always on the lookout for “things you can do now.”  I’m especially happy then when actual clinical trials happen as we can get some idea of the effectiveness of treatments.  About 18 months ago, a paper was published reviewing…

Ameliorating the Adverse Effects of Excess Propionic Acid

I am officially declaring this Biome Buzz’ first annual Propionic Acid Week! (Unfortunately, this is not a cause for celebration.) If you remember, propionic acid (PPA) is a short-chain fatty acid produced by gut bacteria.  Ordinarily, PPA , like the other SCFAs, is great…

Is There Any Doubt Left that Propionic Acid is a Cause of Autism? Apparently not

I first started to write about autism and propionic acid (PPA) not long after creating this blog, back in the fall of 2016.  In January 2017, I described to you some of the work of Dr. Derrick MacFabe, which as particularly fascinated me for…

The Two Sides of Bacteroides fragilis

Back in May, 2018, I wrote about Bacteriodes fragilis (B. fragilis), a species of bacteria some strains of which are toxic, some of which are highly beneficial.  The main thrust of that post was about how our immune system, when functioning properly, can recognize…