Category: Macrobiome

Helminths and Inflammatory Bowel Disease: Some Promising News

Exciting news! It’s been ages since I had any good research on the macrobiome to report to you, and this paper is a all kinds of awesome. To start, the justification for this research: “The increased prevalence of auto-inflammatory conditions, such as diabetes, arthritis,… Continue Reading “Helminths and Inflammatory Bowel Disease: Some Promising News”

Helminths and Gut Bacteria: The Dynamic Anti-Inflammatory Duo

I have some fascinating new research to report to you on helminths, about which I haven’t written in quite awhile.  Last week, in my post about gut bacteria and bile acids, I talked, yet again, about the incredible complexity of the gut ecosystem:  today’s… Continue Reading “Helminths and Gut Bacteria: The Dynamic Anti-Inflammatory Duo”

Biome Depletion in Both Humans and the Environment…Grim News in a Grim Time

Today I’m writing about two articles that are essentially about what we are doing to ourselves as a species.  This post is not an op-ed piece:  this is a simple statement of facts. The first article, out of Washington State University, is about the… Continue Reading “Biome Depletion in Both Humans and the Environment…Grim News in a Grim Time”

The Macrobiome and Mycobiome in IBD: A Look at the Role of “Dirty Old Friends”

A very recent paper, published just this past May, caught my eye because of its title:  “Inflammatory bowel diseases, the hygiene hypothesis and the other side of the microbiota: Parasites and fungi.”[i]  How often on this blog have I talked about the incredible complexity… Continue Reading “The Macrobiome and Mycobiome in IBD: A Look at the Role of “Dirty Old Friends””

Multiple Sclerosis and Helminths: A Phase 2 Clinical Trial

I’m treating myself this week, writing about two of my favorite things:  first a post on “things you can do now,” and now a clinical trial, this one on using helminths to treat multiple sclerosis.[i]  This was a phase 2 study at the University… Continue Reading “Multiple Sclerosis and Helminths: A Phase 2 Clinical Trial”

Helminths in the Time of COVID: A Protective Action?

As soon as I first read about the recognition by physicians that that death from COVID-19 was often caused by a cytokine storm – a massive inflammatory response to an invader, which causes major tissue damage – my first thought was, “I wonder if… Continue Reading “Helminths in the Time of COVID: A Protective Action?”

Obesity, Metabolic Syndrome and Diabetes: Helminths May Hold the Answers

I found a bunch of new research on helminths and will, over the next month or so, make my way through the papers.  I wanted to share first an article just published by researchers in Australia (where some of the best hookworm (Necator americanus)… Continue Reading “Obesity, Metabolic Syndrome and Diabetes: Helminths May Hold the Answers”

Diabetes and Metabolic Disorders: Are Helminths a Solution?

According to the CDC, about 10% of the United States’ population now has diabetes, and 90-95% of those have type 2.[i]  That is tens of millions of people in this country alone, let alone world-wide.  I need you to be sitting when I tell… Continue Reading “Diabetes and Metabolic Disorders: Are Helminths a Solution?”

The Promise of Helminths for Multiple Sclerosis

Today I get to write about something other than the bacterial microbiome!  Woopa! I was very happy to find a new paper on the possibilities of using helminths (helminth immunotherapy (HIT), as these authors call it) to prevent and alleviate multiple sclerosis (MS).[i]  … Continue Reading “The Promise of Helminths for Multiple Sclerosis”

Lupus and Helminths: Preventive Promise?

I continue to monitor the macrobiome space, watching as the evidence (very) slowly but surely continues to mount in support of helminths’ ability to alleviate, or even prevent, the development of autoimmune diseases.  The latest news is that, in an animal model, Japanese researchers… Continue Reading “Lupus and Helminths: Preventive Promise?”