Category: Irritable Bowel Syndrome

The Promise of Fecal Microbiota Transplant

Over the weekend, I read a great little article about the potential applications of fecal microbiota transplant (FMT) in treating a huge variety of diseases.[i]  Of course, we are sorely lacking in clinical trials for almost all but still, there is hope to be…

Probiotics for Chronic Fatigue and Fibromyalgia? Probably, but the Science Isn’t Yet There

As regular readers know, I’m always on the lookout for “things you can do now.”  I’m especially happy then when actual clinical trials happen as we can get some idea of the effectiveness of treatments.  About 18 months ago, a paper was published reviewing…

Irritable Bowel: SIBO, Dysbiosis and Diet

In 2010, I read a paper in the journal, Nutrition, that really rocked my world:  “The concept of small intestinal bacterial overgrowth (SIBO) in relation to functional gastrointestinal disorders.” [i]  To summarize one of its many key points:  we don’t know how to test…

The Microbiome and Mental Illness: An Old Story that is Too Far From its Happy Ending

I just finished reading an article from 2018 on mental health and the microbiome that describes some of where we are now, knowledge-wise, and where we need to be before psychobiotics become a treatment norm.[i]  There were multiple pieces of information in it which…

Introducing Archaea: Another Important Member of Your Inner Ecosystem

It’s not often that I get to write about the more esoteric members of our gut biomes.  Our bacteria get the most hype in the scientific literature, but as you all know, there are many other kinds of residents of our inner ecosystems.  I…

Blastocystis: Harmless or Harmful? The Short Answer is…It Depends!

Here’s a topic I haven’t written about much: single-cell eukaryotes. A eukaryote is a living organism whose cells contain a nucleus (in which genetic material is contained) within a membrane.  Thus, in the world of living things, only bacteria and archaea (which is sort…

More on Autism and the Microbiome…and a Clinical Study Using Probiotics

My Monday afternoon was devoted to reading two articles about the microbiome and autism.  The first was a chapter from a book on biological markers found in psychiatric and neurodegenerative disease.[i]  I’ve chosen what I thought were the top 10 points from this article…

A Probiotic/Colostrum Pilot Study in Autism…Which Likely Has Clinical Implications in Other Inflammatory Illnesses

Yesterday, I read a cool little pilot study[i] out of the University of California, testing the tolerability and efficacy of a probiotic and bovine colostrum on a small group of children with autism.  And while the results on this population were interesting, as I’ll…

Senescence, Aging…and the Microbiome: Part 2

As I promised last Thursday, I’ll finish talking about the article[i] on aging, the microbiome,  and senescence today. A quick summary of my last post:  the evidence currently available points to a depletion of the microbiota as we age (from diet (for example, older…

More on Boosting Levels of Short-Chain Fatty Acids

While I’m on the subject of butyrate… An article[i] was published in the International Journal of Pharmaceutics that caught my attention.  Researchers tested the efficacy of a probiotic (one I had never heard of) called, Symprove . One of the big issues often raised about…