Inflammatory Bowel Disease and Diet – Irrevocably Linked

This morning, I got all excited when I spotted the headline in IBD News Today, “Natural Diet is Key to Preventing, Reversing Crohn’s in Children, Israeli Expert Says.”[i]  Wow! I hoped that this article would be about the Specific Carbohydrate Diet, or at least something close to it (bearing in mind the recent work by … More Inflammatory Bowel Disease and Diet – Irrevocably Linked

Immune Tolerance and Pathobionts: Good Guys/Bad Guys

Did you ever wonder how our bodies are able to differentiate between our commensal bacteria and pathogenic ones?  Many times in this blog, I’ve written about this “immune tolerance.”   Researchers at NYU are trying to figure this out and are partly there.[i] Of course, what makes this even more complicated is that some bacteria are … More Immune Tolerance and Pathobionts: Good Guys/Bad Guys

New Information on the Microbiome and Neurodegenerative Diseases

Yet more research[i] has just been published showing the bacterial microbiome’s connection to neurodegenerative diseases like Alzheimer’s and Parkinson’s.  A variety of bacteria (including ones found in the mouth) produce amyloid proteins (known as bacterial amyloids) similar to the ones produced naturally by our neurons.  (Remember, as I’ve described in a previous post, that amyloid … More New Information on the Microbiome and Neurodegenerative Diseases

You Read It Hear First: Protozoa the Next Generation Probiotic

Helminths are not the only macrobiotic organism that resides in the human ecosystem.  Today, we’re talking protozoa. I read a paper yesterday that has me beside myself with excitement.  (I really do need to get out more.)   “Gut Protozoa:  Friends or Foes of the Human Gut Microbiota?”[i] The authors argue “…that protozoa, like helminths, represent … More You Read It Hear First: Protozoa the Next Generation Probiotic

Dietary Carbohydrates, Bowel Disease and the Bacterial Microbiome

Feeling nostalgic after last week’s post on autism and carbohydrate malabsorption, I spent some time today flipping through one of my massive binders of research that I’ve been collecting for the last 20 years.  After Alex’s amazing response to the Specific Carbohydrate Diet, I began to look carefully at research supporting its use and it … More Dietary Carbohydrates, Bowel Disease and the Bacterial Microbiome

Impaired Carbohydrate Digestion, Bacterial Dysbiosis and Autism…the Unfinished Story

I have to say,  I really hate it when a really exciting bit of research is just dropped.  It’s like having a TV show you like cancelled mid-season…and you’re just kind of left hanging…forever…. As it’s Thursday, I thought I’d to a TBT, and tell you about a paper that I have been brooding about … More Impaired Carbohydrate Digestion, Bacterial Dysbiosis and Autism…the Unfinished Story

The Bacterial Microbiome and (Male) Brain Development

A new study out of Singapore suggests that alterations in the microbiome affect the development of the brain’s immune system (the microglia) in males more than females.[i] The microglia defend against pathogens in the brain, and clear out debris.  They are also partially responsible for brain development of neuronal connections.  Autism is known to be … More The Bacterial Microbiome and (Male) Brain Development

Helminths and a New Kind of Industrial Revolution

In August, 2017,  researchers gave TSO (porcine whip worm, Trichuris suis ova), to a man with psoriasis, who was otherwise healthy.  They then examined the effects of the helminth via colonoscopy and blood work, discovering that there were profound immunological changes in the area where the TSO live, limited changes in the other parts of … More Helminths and a New Kind of Industrial Revolution

Early Life Immune Activation, Autism, and Seizures

For all you other parents of children with epilepsy and/or autism and/or other related developmental issues, some pretty depressing – but also, extremely important – research was just published by scientists at McLean Hospital:  “…even a brief episode of immune system activation within days of birth can cause persistent changes in sleep patterns concurrent with … More Early Life Immune Activation, Autism, and Seizures