The Prophylactic Use of Probiotics (to Combat Microbiome Alterations Due to C-section and Early Life Antibiotic Use)

The article I read yesterday was a natural follow-on from my last post, about autism and its relationship to perturbations in the gut microbiome. This one was about a double-blind, placebo-controlled study using probiotics to restore normal gut microbiota in infants who were either born via c-section or given antibiotics early in life.[i] Before I … Read more

Autism and the Microbiome: A Summary of What We Know Now

Two days ago, I spotted a short commentary[i] in the journal, International Journal of Molecular Sciences, from this past August, which really caught my attention. Here is why:  it was written by 3 researchers in the department of neurology at Rutgers University’s medical school who state that, “We will explore the potential for treatment of … Read more

More on Boosting Levels of Short-Chain Fatty Acids

While I’m on the subject of butyrate… An article[i] was published in the International Journal of Pharmaceutics that caught my attention.  Researchers tested the efficacy of a probiotic (one I had never heard of) called, Symprove . One of the big issues often raised about probiotics:  will the bacteria survive stomach acid to reach the intestines?  … Read more

Stress and Our Missing Old Friends

Yesterday I devoted several hours to reading a fascinating article on the connection between stress and the microbiome.[i]  The conclusion:  the lack of exposure to our “old friends” (those commensal organisms with which humans co-evolved) has caused immune dysregulation, leading to a greater susceptibility to the adverse effects of stress…and that stress, in turn, has … Read more

Helminths and Allergies: Another Look at an Immigrant Population

In my last post, I talked about how microbiome depletion results from immigrating to the United States (and subsequent dietary changes), which leads to obesity and metabolic diseases.  I promised to tell you more about immigrant studies on biome depletion so today I am addressing a paper from 2 years ago in which researchers describe … Read more

The Negative (Biome) Side of Moving to the USA

Last week, a really interesting new study[i] was published in the journal, Cell, detailing how immigrating to the USA negatively impacts the gut bacteria.  Researchers looked at people from Southeast Asia and found that there was a significant reduction in the diversity of gut microbes with each subsequent generation, culminating with their microbiota resembling those of … Read more